Attwater Research Group

Research Team

Interested in undergraduate/Master’s laboratory experience and training at the interface of organic chemistry and molecular biology? Please email to discuss potential research placements or projects in our group.

We are open to supporting applications for postdoctoral fellowships if you have a compelling vision for research that you would like to explore within my group – get in touch and we can explore candidate/idea/funder fit. We particularly welcome applicants from under-represented backgrounds.

James Attwater

Lecturer in Organic Chemistry and Chemical Biology (proleptic). Royal Society University Research Fellow.

I am interested in the nature of minimal biological systems, both synthetic and primordial. I completed my PhD studies in Philipp Holliger’s lab at the MRC Laboratory of Molecular Biology, Cambridge, where I developed and characterised new catalytic RNAs using molecular evolution. I continued my postdoctoral work at the LMB as a Junior Research Fellow of Homerton College Cambridge, then as Investigator Scientist, exploring biological behaviours in these molecular systems. I took up a Royal Society University Research Fellowship in 2021 to begin my independent research into the synthetic capabilities of RNA in a prebiotic chemical context.

Qian Zhang

Postdoctoral Research Fellow in RNA catalysis

I joined James’s lab in late 2023 to investigate the abundance of miniature RNA motifs and their capacity to drive biological and prebiotic chemical transformations. I am currently completing my DPhil studies in Andrew Turberfield’s lab at the University of Oxford. My doctoral work focuses on oligonucleotide-based molecular machines as part of the Marie Curie network ArtMoMa. During my DPhil studies, I visited Philipp Holliger’s lab at the MRC Laboratory of molecular biology, where I learned more about in vitro selection and got interested in the origins of life.

Joshua Maiklem

3rd year PhD student

I read Natural Sciences at Cambridge, specialising in chemistry, and completed my masters project in the Balasubramanian Lab, studying the molecular recognition of epigenetic markers. Within my PhD research I am focusing on the influence of amino acids upon RNA-catalysed RNA synthesis. In my free time I enjoy climbing and running, organising the department’s postgraduate run club.

Luis Ohlendorf

2nd year PhD student

For my BSc and MPhil, I worked on SARS-CoV-2 evolution and vaccine development (Regensburg University and University of Cambridge). I am interested in the interactions between different RNA species in a hypothetical RNA world, the catalytic capabilities of RNA, and general questions about the origin of life and evolution. 

Attwater Research Group

UCL Department of Chemistry,
20 Gordon Street,
London WC1H 0AJ

j.attwater[at]ucl.ac.uk